Chromosomal abnormalities and embryo development in recurrent miscarriage couples

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Chromosomal abnormalities and embryo development in recurrent miscarriage couples.

BACKGROUND Chromosomal abnormalities are an important cause of spontaneous abortion and recurrent miscarriage (RM). Therefore, we have analysed the incidence of chromosomal abnormalities and embryo development in patients with RM. METHODS Preimplantation genetic diagnosis (PGD) was performed on 71 couples with RM and 28 couples undergoing PGD for sex-linked diseases (control group). Chromosom...

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Evaluation and Contribution of Major Chromosomal Abnormalities in Couples with Recurrent Miscarriage

Background: Pregnancy loss is a common phenomenon. Most of the pregnancy losses which happen in the first and second trimesters are caused by chromosomal abnormalities. Repeated pregnancy loss is an extremely stressful condition for both the partners and physicians because it is difficult to find a reason behind it. Materials and Methods: Cytogenetic analysis was performed according to standard...

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Structural chromosomal abnormalities in couples with recurrent abortion in Egypt.

BACKGROUND/AIM To evaluate the incidence of chromosomal abnormalities in couples who experience recurrent abortion and identify additional factors that may be predictive of abortion, such as parental age and unfavorable obstetric or abnormal semen analysis. MATERIALS AND METHODS The present study examined 125 couples who had experienced recurrent abortion. All subjects provided a detailed per...

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Chromosomal abnormalities in 163 Tunisian couples with recurrent miscarriages

Recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses before 24 weeks of gestation. Parental chromosomal abnormalities represent an important etiology of RM. The aim of the present study was to identify the distribution of chromosome abnormalities among Tunisian couples with RM referred to the Department of Cytogenetic at the Pasteur Institute of Tunis (Tunisia) du...

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Chromosomal abnormalities in couples with recurrent first trimester abortions.

PURPOSE To investigate the prevalence of chromosomal abnormalities in couples with two or more recurrent first trimester miscarriages of unknown cause. METHODS The study was conducted on 151 women and 94 partners who had an obstetrical history of two or more consecutive first trimester abortions (1-12 weeks of gestation). The controls were 100 healthy women without a history of pregnancy loss...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2003

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/deg015